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NEURODEGENERATIVE
DISEASES

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Our brain consists of millions of nerve cells which have a versatile control over the innumerable electrical signals that enables us to sustain routine undertakings. These nerve cells transmit signals from the external surroundings to our muscles via the Central Nervous System and initiate movements thus fuelling to one’s survival. Whenever these nerve cells fail to meet the required requisites and stop functioning, neurodegenerative diseases occur. Even though the proper functioning of the nerve cells is vital for survival, researchers are unable to come up with a cure that would lead to their out-and-out eradication. At the subatomic level, biomedical research has revealed the existence of a good deal of connections between these disorders; including aberrant protein assemblages like proteinopath and triggered cell death. Because of these commonalities, it is possible that therapeutic developments for one neurodegenerative disease will also benefit other diseases. 

Research has proven that inflammation and oxidative stress are the two main causes of neurodegeneration. However, no investigated means to stop the ongoing deterioration of neurons has been developed. Only treatment that may relieve a fraction of the physical and mental repercussions to a certain extent has been brought into light. Slowing down the progression of the various conditions falling under neurodegenerative diseases has not been possible due to lack of treatment which further necessitates the provision of extensive studies with potential for outright liquidation. Developing new approaches for its prevention and treatment can rather be viewed as the need of the hour. A human being comprises genes which can be analysed in a rigorous manner and the information gathered can be put to use in understanding the overall contribution to the developing risk of such a condition. The external environmental factors when combined with the genetic factors can provide clarity to the treatment’s approach. It is possible for an individual to consist of genes making them susceptible to various neurodegenerative diseases such as Alzheimer’s, Parkinson’s, MND (Motor Neurone Disease) or Amyotrophic lateral sclerosis (ALS).
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